{"id":1726,"date":"2022-06-27T11:00:25","date_gmt":"2022-06-27T09:00:25","guid":{"rendered":"https:\/\/cosmetosciences.fr\/non-invasive-method-for-personalising-dermocosmetic-treatments\/"},"modified":"2022-12-06T16:48:53","modified_gmt":"2022-12-06T15:48:53","slug":"non-invasive-method-for-personalising-dermocosmetic-treatments","status":"publish","type":"post","link":"https:\/\/cosmetosciences.fr\/en\/non-invasive-method-for-personalising-dermocosmetic-treatments\/","title":{"rendered":"Non-invasive method for personalising dermocosmetic treatments"},"content":{"rendered":"\n\n[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; top_divider_style=&#8221;curve&#8221; top_divider_color=&#8221;#8FB459&#8243; top_divider_height=&#8221;9px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;Comfortaa||||||||&#8221; header_font_size=&#8221;34px&#8221; header_2_font=&#8221;Comfortaa|700|||||||&#8221; header_2_text_align=&#8221;center&#8221; header_2_line_height=&#8221;1.2em&#8221; global_colors_info=&#8221;{}&#8221;]<h1>MINIONS\nNon-invasive methods for personalising dermocosmetic treatments\n<\/h1>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-8px|auto||auto||&#8221; custom_padding=&#8221;4px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||on||||||&#8221; text_font_size=&#8221;18px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<p>The effectiveness of cosmetic products involves the controlled penetration into the skin of the active compounds they contain. Knowing the composition and morphology of the skin barrier is essential to understanding the mechanisms of diffusion of cosmetic active compounds.\nFor this reason, the development of non-invasive analytical tools describing the skin barrier function is a major challenge that offers prospects for the personalisation of topical treatments.\n<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;Comfortaa|700|||||||&#8221; header_2_line_height=&#8221;1.2em&#8221; global_colors_info=&#8221;{}&#8221;]<h2>Multimodal approach for the design of cosmetic products adapted to all skin types\n<\/h2>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/cosmetosciences.fr\/wp-content\/uploads\/2022\/05\/spectroscopie-raman-cosmetique.jpg&#8221; alt=&#8221;Use of Raman spectroscopy&#8221; title_text=&#8221;spectroscopy-raman-cosmetics&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;15px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<p>This project on the personalisation of dermocosmetic treatments is based on the creation of a multimodal analytical approach, combining Raman spectroscopy, high resolution and photoacoustic ultrasound imaging and biological studies to collect biochemical (hydration, lipids, proteins, etc.) and histological (thickness and organisation of skin layers) information from in vivo human skin.\n\nTaking into account this information and the physicochemical properties of the cosmetic forms, correlative mathematical models for predicting the diffusion kinetics of the cosmetic active compounds will be proposed. \n\nUltimately, being able to understand the condition of the barrier function through rapid analysis will make it possible to design products to suit every skin type for an optimal effect.\n<\/p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;Comfortaa|700|||||||&#8221; header_2_line_height=&#8221;1.2em&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<h2>Custom personalisation of dermocosmetic treatments with plasma spray\n<\/h2>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;15px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]The personalisation of dermocosmetic skin treatments will be reinforced by the development of a new generation of plasma spray technologies that will be able to modulate the physicochemical properties of topical treatments without disrupting or mechanically altering the barrier function.\n\nChanges in molecular interactions at skin level due to the application of cosmetic active compounds in the form of plasma spray could act on their behaviour in relation to their skin penetration and these action mechanisms need to be studied for a better understanding and optimisation of the delivery of cosmetic active compounds.\n\nThe innovative combination of plasma spray and Raman spectroscopy on in-vivo skin will allow optimisation of the application conditions and therefore custom personalisation of dermocosmetic treatments.[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#f2f2f2&#8243; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_radii=&#8221;off||20px|20px|&#8221; border_width_left=&#8221;6px&#8221; border_color_left=&#8221;#969696&#8243; global_colors_info=&#8221;{}&#8221;]<span class=\"titreprojet\">Project partners<\/span>\n\n<strong>4 ACADEMIC laboratories<\/strong>\n<ul>\n\t<li>NMNS (EA6295 \u2013 University of TOURS)<\/li>\n\t<li>IBRAIN (U1253 \u2013 INSERM)<\/li>\n\t<li>GREMI (UMR7344 \u2013 University of ORL\u00c9ANS)<\/li>\n\t<li>CBM (UPR4301 \u2013 CNRS ORL\u00c9ANS)<\/li>\n<\/ul>\n<strong>3 INDUSTRIAL partners<\/strong>\n<ul>\n\t<li>Transderma Systems, TOURS (37)<\/li>\n\t<li>Spincontrol, TOURS (37)<\/li>\n\t<li>Laboratories ERIGER, TOURS (37)<\/li>\n<\/ul>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(200,179,163,0.66)&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_radii=&#8221;off||20px|20px|&#8221; border_width_left=&#8221;6px&#8221; border_color_left=&#8221;#7D5A40&#8243; global_colors_info=&#8221;{}&#8221;]<span class=\"titreprojet\"> Recruitment<\/span>\n<ul>\n\t<li>4 post-doctoral researchers<\/li>\n\t<li>Le Studium international researcher:\nRecruitment in progress\u2026<\/li>\n<\/ul>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.17.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(143,180,89,0.52)&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_radii=&#8221;off||20px||&#8221; border_width_left=&#8221;6px&#8221; border_color_left=&#8221;#8FB459&#8243; global_colors_info=&#8221;{}&#8221;]<p><span class=\"titreprojet\">Funding<\/span><\/p>[\/et_pb_text][et_pb_number_counter title=&#8221;K\u20ac over 3 years&#8221; number=&#8221;912&#8243; percent_sign=&#8221;off&#8221; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; number_font=&#8221;Comfortaa||||||||&#8221; number_text_color=&#8221;#8FB459&#8243; background_color=&#8221;rgba(143,180,89,0.52)&#8221; custom_margin=&#8221;||0px||false|false&#8221; border_width_left=&#8221;6px&#8221; border_color_left=&#8221;#8FB459&#8243; global_colors_info=&#8221;{}&#8221;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(143,180,89,0.52)&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_radii=&#8221;off|||20px|&#8221; border_width_left=&#8221;6px&#8221; border_color_left=&#8221;#8FB459&#8243; global_colors_info=&#8221;{}&#8221;]<p>for regional (ARD CVL)<\/p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(221,152,166,0.47)&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_radii=&#8221;off||20px|20px|&#8221; border_width_left=&#8221;6px&#8221; border_color_left=&#8221;#DD98A6&#8243; global_colors_info=&#8221;{}&#8221;]<span class=\"titreprojet\">Contact<\/span>\n<strong>Franck BONNIER\n<\/strong>NMNS (EA6295 \u2013 University of TOURS)\n\n<a href=\"mailto:franck.bonnier@univ-tours.fr\"><strong>franck.bonnier@univ-tours.fr<\/strong><\/a>\n\n<strong>Emilie MUNNIER \n<\/strong>NMNS (EA6295 \u2013 University of TOURS)\n\n<a href=\"mailto:emilie.munnier@univ-tours.fr\"><strong>emilie.munnier@univ-tours.fr<\/strong><\/a>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n\n\r\n","protected":false},"excerpt":{"rendered":"<p>The effectiveness of cosmetic products involves the controlled penetration into the skin of the active compounds they contain. Knowing the composition and morphology of the skin barrier is essential to understanding the mechanisms of diffusion of cosmetic active compounds.<\/p>\n","protected":false},"author":1,"featured_media":706,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[174],"tags":[189,190,191,192,193],"class_list":["post-1726","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-in-progress-2020-2023","tag-personalisation","tag-dermocosmetic-treatments","tag-plasma-spray","tag-raman-spectroscopy","tag-in-vivo-evaluation-of-biological-activity"],"acf":[],"_links":{"self":[{"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/posts\/1726","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/comments?post=1726"}],"version-history":[{"count":2,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/posts\/1726\/revisions"}],"predecessor-version":[{"id":1997,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/posts\/1726\/revisions\/1997"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/media\/706"}],"wp:attachment":[{"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/media?parent=1726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/categories?post=1726"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cosmetosciences.fr\/en\/wp-json\/wp\/v2\/tags?post=1726"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}